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Original Article
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Korean J Fertil Steril. 1990;17(1):57-63.
- Study on Pregnancy and Improvement of Fertilization rate by Micromanipulation (Partial Zona Dissection (PZD) and Micro-Insemination by Sperm Transfer(MIST) in human IVF-ET
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Ho-Joon Lee1, Kyoo-Wan Choi1, Jong-Yung Jun1, Jong-Min Park1, Hyuck-Chan Kwon1, Moon-Kyoo Kim2
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1IVF Research Laboratory, Department of Obstetrics and Gynecology, Cheil General Hospital
2Department of Biology, College of Natural Science, Hanyang University
- Abstract
- The purpose of this study is to improve fertilization rate in IVF-ET program of patients with male infertility used micromanipulation technique, partial zona dissection (PZD) or micro-insemination by sperm transfer (MIST). The results were as follows 1. The fertilization rate of non-micromanipulated oocytes and micromanipulated (PZD) oocytes were 12.5% (n=2) and 42.2% (n=19), respectively, and showed significant differences between two groups (p<0.05). 2. The fertilization rate of micromanipulated (MIST) oocytes was 30% (n=27). 3. The damage rate of Group 1 (PZD) and Group 2 (MIST) were 15.7% (3/19) and 29.6% (8/27), respectively. 4. One pregnancy resulted following replacement of micromanipulated (MIST) embryos in 4 patients.
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